Middle-aged zoo worker Natasha still lives with her mother in a small coastal town. She is stuck and it seems that life has no surprises for her until one day - she grows a tail and turns her life around.
A shy student trying to reach his family in Ohio, a gun-toting tough guy trying to find the last Twinkie, and a pair of sisters trying to get to an amusement park join forces to travel across a zombie-filled America.
Americans on vacation in the Caribbean take a tour of a nearby island at night and watch a local voodoo ritual. Soon after, they find themselves stranded on the island and under attack by unseen foes. One by one they meet violent ends.